huahana

Estradiol valerate CAS: 979-32-8

Ka wehewehe kikoʻī

ʻO Megestrol kahi progestogen ikaika. Hoʻohana ʻia ʻo Megestrol i ka hui pū ʻana me ka waha maʻa a e like me ka mea antineoplastic agent.


Hōʻike huahana

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ʻO keʻano

Estradiol valerate (EV, E2V) (INN, USAN, JAN) (inoa inoa inoa ʻo Altadiol, Deladiol, Delestrogen, Estraval, Lastrogen, Progynova, Valergen, he nui wale aku), a i ʻole oestradiol valerate (BAN), he mea hana estetika synthetic, kūikawā o ka 17 -pentanoyl ester, of the natural estrogen, 17β-estradiol. Ua hoʻohauna mua ʻia ʻo ia, ʻo Delestrogen e Squibb i United States, i ka makahiki 1954, a me ka estradiol benzoate (1936) a me ka estradiol cypionate (1952), i lilo ia i mea nui o nā esters e hoʻohana ʻia no ka estradiol.
Ma ka ingestion, ma kahi o ke ala o ka hoʻokele ʻana, e kūleʻa ana ʻo estradiol valerate e like me ka prodrug, i hoʻopuni ʻia e nā esterases ma ka lolo koko a me ka ate i ka 17β-estradiol a me ka valeric acid. Eia nō naʻe, hoʻohālikelike ʻia me ka estradiol ponoʻī, ua pānaʻi pinepine ʻia ka estradiol valerate a loaʻa iā ia ka lōʻihi, ʻoi aku hoʻi i ka wā i hāʻawi ʻia i loko o ka hopena o ka aila ma o ka intramuscular injection (ma loko o kahi hana he depot). ʻO ka hopena, hiki ke hoʻokele pinepine ʻia.
Kahi kikowaena intramuscular o 4mg estradiol valerate hopena i nā kiʻekiʻe plasma pae kiʻekiʻe o ka estradiol ma kahi o 390 pg / mL i loko o ʻekolu lā o ka hoʻokele ʻana, me nā pae i emi i 100 pg / mL ma nā lā 12-13. ʻO kahi hōʻike o ka hoʻokele hui pū ʻana o 40mg estradiol valerate a me 250mg hydroxyprogesterone caproate i loko o nā wahine i hoʻokahi manawa i hoʻokahi mau mahina noʻeono mau mahina (ua hōʻike ʻia he “pseudopregnancy” regimen) loaʻa i nā pae serum o ka estradiol i hoʻonui ʻia mai 27.8-34.8 pg / mL i 3028–3226 pg / mL ma hope o ʻekolu mahina a i ka 2491–2552 pg / mL ma hope o ʻeono malama o ka mālama ʻana.

Ka ʻike kumu

ʻAno Kūmole Estradiol 17-Palapala
Puʻuwai Estradiol valerate;
CAS ʻAʻole. 979-32-8
Puka Ilahi C23H32O3
Ke kaumaha Maʻamau 356.49800
PSA 46.53000
Hoʻopuka 5.35030

ʻŌnaehana helu helu

UNII OKG364O896

Pono waiwai

Kainoʻao a me ke Aupuni Moʻomanaʻo Na
ʻĀina wai 1.13g / cm3
Papa Ola 486.2ºC i 760mmHg
ʻOihana Hoʻolaha 144ºC
Ke Alaula 191.1ºC
Ho‘ololi Huahelu 1,567

ʻO ka ʻike ʻikepili

ʻO RTECS KG5793000
Nā ʻōlelo palekana S53-S45
WGK Kelemania 3
Nā Palapala Hoʻoikaika R60; R61
Nā Kuhi Hōʻailona T

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Kālā huahana

_MG_4750

 

Nā huahana kaulana

100-09-4 4-methoxybenzoic acid 23076-35-9 Xylazine hydrochloride
138-59-0 Shikimic acid 56786-63-1 5A-Hydroxy Laxogenin
1451-83-8 2-Bromo-4-Methylpropi 103-81-1 2-phenylacetamide
6080-56-4 alakaʻi diacetate trihydrate 131707-25-0 Arbidol
62-44-2 fenacetn 137-58-6 Coverocaine
94-09-7 benzocaine 148553-50-8 pregabalin
94-15-5 Dimethocaine 16595-80-5 Levamisole hcl
136-47-0 ʻIkia kahikina Tetracaine 81646-13-1 Nāihana Btms
23239-88-5 ʻO Benzocaine Hydrochloride 78-67-1 AIBN-64
593-51-1 methylamine hydrochloride 94-24-6 Tetracaine
73-78-9 hyhuchloride hapikuha 2893-78-9 SDIC
99-92-3 4-Aminoacetophenone 4584-49-0 2-Dimethylaminoisopropyl Chloride
41979-39-9 4-oxopiperidinium chloride 49851-31-2 α-Bromovalerophenone
40064-34-4 4-Piperidon 5337-93-9 4-methylpropiophenone
705-60-2 Phenyl-2-nitropropene 459-03-0 4-Fluorophenylacetone
37148-47-3 4-Amino-3,5-dichlorophenacylbromide 49851-31-2 2-Bromo-1-phenyl-1-pentanone
37148-48-4 4-Amino-3,5-dichloroacetophenone 600-00-0 Ethyl 2-Bromoisobutyrate
23426-63-3 tīleʻa methyl 2-bromo-2-methylpropanoate 5445-19-2 Methyl 2-Bromohexanoate
64-17-5 Ethanol 100-07-2 4-Methoxybenzoyl klorida
96-48-0 γ-Butyrolactone 103-63-9 (2-Bromoethyl) benzene
9003-01-4 Ka waikawa polyacrylic 9007-20-9 Kāleka
54182-57-9 Kālo (8CI)    

 

Hui a ʻoihana kemana

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Mahalo i kou noʻonoʻo ʻana no Hebei Shuoxi Biotechnology Co., Ltd (HBSX). ʻO HBSX kahiʻoihana wikiwiki e ulu ulu ana, aia ma Shijiazhuang, Hebei Province.
He hana kūikawā ʻo HBSX i kahi lāʻau lapaʻau i waena o nā lāʻau lapaʻau, nā mea hoʻonaninani lāʻau lapaʻau a me nā mea kikowaena dyes, e like me ka phenylacetamide, dimethylamine hcl, benzyl chloride etc., ʻo HBSX hoʻolako pū i nā meakanu ʻoihana ʻenehana no nā mea kūʻai, e like me ka citric acid, potassium chloride etc.
Ma hope o ka hoʻomohala ʻumi mau makahiki, ua lilo ʻo HBSX i kahi ʻoihana hoʻomohala Diversified, ʻaʻole pili wale i nā kemika, akā, ʻo ka waiwai, nā lole, nā huahana mahiʻai a pēlā aku.
Ma kēia manawa, ʻo HBSX kahi ʻoihana ma kahi o 35 mau ʻāina, ʻo ka hapa nui o nā mea kūʻai nui e hele mai mai Europa a me ʻAmelika, no ka mea i waena o nā mea lako ma china, hiki iā HBSX ke hana i ka maikaʻi o ka huahana, hiki i kekahi o nā huahana mai ka HBSX ke hiki i ka maʻemaʻe o 99.9+ , penei i 2-phenylacetamide. ʻO ia ke kumu nui o nā mea kūʻai aku e koho ana i ka HBSX.
I ka wā e hiki mai ana, pono ʻo HBSX i kahi ʻoihana kālepa nui loa no ka china a me nā ʻāina ʻē i ka waiwai me nā ʻoihana lapaʻau.

 

ʻOhiʻohi

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